In this episode on Mara Labs, Dr. John Gildea and David Roberts interview Dr. Jesse Myers and discuss the medicinal properties of the bio-active polyphenol called curcumin and a wide variety of other topics including root canals, the oral microbiome, how oral health impacts Alzheimer's disease, fluoride, Dr. Myers' favorite toothpaste, and much more!
(Mara Labs is the creator of CurcElite®, one of Dr. Myers' personal favorite supplements, which is a highly bioavailable curcumin supplement that contains curcumin and Mara Labs patented carrier molecule, which increases the bioavailability of the curcumin.)
Check out the interview below to learn more!
References:
Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis
Zhang Y, Huang L, Zhang J, De Souza Rastelli AN, Yang J, Deng D. Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:808460. Published 2022 Jan 24. doi:10.3389/fphar.2022.808460
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis
Kitamoto S, Nagao-Kitamoto H, Jiao Y, et al. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. Cell. 2020;182(2):447-462.e14. doi:10.1016/j.cell.2020.05.048
Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota
Teng Y, Ren Y, Sayed M, et al. Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota. Cell Host Microbe. 2018;24(5):637-652.e8. doi:10.1016/j.chom.2018.10.001
Efficacy of curcumin as an adjunct to scaling and root planning in chronic periodontitis patients: A clinical and microbiological study
Nagasri M, Madhulatha M, Musalaiah SV, Kumar PA, Krishna CH, Kumar PM. Efficacy of curcumin as an adjunct to scaling and root planning in chronic periodontitis patients: A clinical and microbiological study. J Pharm Bioallied Sci. 2015;7(Suppl 2):S554-S558. doi:10.4103/0975-7406.163537
The impact of the stone age diet on gingival conditions in the absence of oral hygiene
Baumgartner S, Imfeld T, Schicht O, Rath C, Persson RE, Persson GR. The impact of the stone age diet on gingival conditions in the absence of oral hygiene. J Periodontol. 2009;80(5):759-768. doi:10.1902/jop.2009.080376
Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
Dominy SS, Lynch C, Ermini F, et al. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019;5(1):eaau3333. Published 2019 Jan 23. doi:10.1126/sciadv.aau3333
Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins
Nonaka S, Kadowaki T, Nakanishi H. Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins. Neurochem Int. 2022;154:105282. doi:10.1016/j.neuint.2022.105282